Molecular dynamics simulations of the Salmonella typhi Vi antigenic polysaccharide and effects of the introduction of a zwitterionic motif
β Scribed by Legnani, Laura; Compostella, Federica; Grazioso, Giovanni; Albini, Franca Marinone; Toma, Lucio
- Book ID
- 118203262
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 664 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1477-0520
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## Abstract In this paper, a convenient approach to the synthesis of the repeating Ξ±β(1β4)βlinked __N__βacetyl galactosaminuronic acid units from the capsular polysaccharide of __Salmonella typhi__ is reported. The exclusively Ξ±βstereoselective glycosylation reactions were achieved by using oxazoli
## RNase A has been extensively used as a model protein in several biophysical and biochemical studies. Using the available structural and biochemical results, RNase A-UpA interaction has been computationally modeled at an atomic level. In this study, the molecular dynamics (MD) simulations of nativ