Use of Molecular-Dynamics Simulation for
β
Moritz Winger; Wilfredβ
F. vanβ
Gunsteren
π
Article
π
2008
π
John Wiley and Sons
π
German
β 690 KB
## Abstract In earlier work, two highly homologous (87% sequence identity) ankyrin repeat (AR) proteins, E3\_5 and E3\_19, were studied using molecularβdynamics (MD) simulation. Their stabilities were compared, and it was found that the Cβterminal capping unit is unstable in the protein E3\_19, in