Molecular Dynamics Simulations of C2F6 Effects on Gramicidin A: Implications of the Mechanisms of General Anesthesia
โ Scribed by Liu, Zhanwu; Xu, Yan; Tang, Pei
- Book ID
- 119919224
- Publisher
- Biophysical Society
- Year
- 2005
- Tongue
- English
- Weight
- 386 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0006-3495
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๐ SIMILAR VOLUMES
Gramicidin A (gA) is prototypical peptide antibiotic and a model ion channel former. Configured in the solid-state NMR beta(6.5)-helix channel conformation, gA was subjected to 1-ns molecular dynamics (MD) gas phase simulations using the all-atom charmm22 force field to ascertain the conformational
## Abstract The effects of gramicidin A (GA) peptide on the structure of lipid bilayer were studied by molecular dynamics (MD) simulations in the absence and presence of GA peptide. The hydrophobic match between the GA and surrounding lipid bilayer was investigated by the MD simulations of four kin