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Molecular dynamics simulations of a branched tetradecasaccharide substrate in the active site of a xyloglucan endo -transglycosylase

✍ Scribed by Mark, Pekka; Zhang, Qiong; Czjzek, Mirjam; Brumer, Harry; Ågren, Hans


Book ID
120471715
Publisher
Taylor and Francis Group
Year
2011
Tongue
English
Weight
491 KB
Volume
37
Category
Article
ISSN
0892-7022

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✍ Oliver S. Smart; John Akins; Dr. David M. Blow 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 946 KB

## Abstract A proposed reaction mechanism for the enzyme D‐xylose isomerase involves the ring opening of the cyclic substrate with a subsequent conformational rearrangement to an extended open‐chain form. Restrained energy minimization was used to simulate the rearrangement. In the ring‐opening ste