Molecular Dynamics Simulation of 8-Oxoguanine Containing DNA Fragments Reveals Altered Hydration and Ion Binding Patterns.

Molecular dynamics simulation of cluster

Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site

✍ Hirofumi Fujimoto; Miroslav Pinak; Toshiyuki Nemoto; Peter O'Neill; Etsuo Kume; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 479 KB 👁 1 views

## Abstract Clustered DNA damage sites induced by ionizing radiation have been suggested to have serious consequences to organisms, such as cancer, due to their reduced probability to be repaired by the enzymatic repair machinery of the cell. Although experimental results have revealed that cluster