𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular domains of myelinated axons in the peripheral nervous system

✍ Scribed by James L. Salzer; Peter J. Brophy; Elior Peles

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
505 KB
Volume
56
Category
Article
ISSN
0894-1491

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Myelinated axons are organized into a series of specialized domains with distinct molecular compositions and functions. These domains, which include the node of Ranvier, the flanking paranodal junctions, the juxtaparanodes, and the internode, form as the result of interactions with myelinating Schwann cells. This domain organization is essential for action potential propagation by saltatory conduction and for the overall function and integrity of the axon. Β© 2008 Wiley‐Liss, Inc.

πŸ“œ SIMILAR VOLUMES

Axonal modulation of myelin gene express
Axonal modulation of myelin gene expression in the peripheral nerve
✍ A. C. LeBlanc; Dr. J. F. Poduslo πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 951 KB

Myelin gene expression (Po, MBP, P,, and MAG) was investigated during Wallerian degeneration and in the presence or absence of subsequent axonal regeneration and remyelination. The steady state levels of mRNA and protein were assessed in the crushed or permanently transected rat sciatic nerve at 0,

Laminin overrides the inhibitory effects
Laminin overrides the inhibitory effects of peripheral nervous system and central nervous system myelin-derived inhibitors of neurite growth
✍ Dr. S. David; P. E. Braun; D. L. Jackson; V. Kottis; L. McKerracher πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 895 KB

## Abstract Axon growth inhibitory proteins associated with central nervous system (CNS) myelin are responsible in part for the absence of long distance axon regeneration in the adult mammalian CNS. We have recently reported that myelin‐associated glycoprotein (MAG), which is also present in periph

BDNF overexpression produces a long-term
BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system
✍ Ravi J. Tolwani; JosΓ© M. Cosgaya; Sushama Varma; Reza Jacob; Lydia E. Kuo; Eric πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 304 KB

## Abstract The neurotrophin brain‐derived neurotrophic factor (BDNF) is an endogenous regulator of the myelination process during development in the peripheral nervous system. Enhancement of myelin formation by BDNF is mediated by the neurotrophin receptor p75^NTR^. Although this neurotrophin is a

Characterization of peripheral myelin pr
Characterization of peripheral myelin protein 22 in zebrafish (zPMP22) suggests an early role in the development of the peripheral nervous system
✍ Philip Wulf; Robert R. Bernhardt; Ueli Suter πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 373 KB πŸ‘ 2 views

Peripheral myelin protein 22 (PMP22) is a component of compact myelin of the peripheral nervous system (PNS). Mutations affecting PMP22 are associated with hereditary neuropathies in humans and rodents. Although mammalian PMP22 is expressed in several tissues, the disease pathology is restricted to