Molecular determinants of human uveal melanoma invasion and metastasis
โ Scribed by Elisabeth A. Seftor; Paul S. Meltzer; Dawn A. Kirschmann; Jacob Pe'er; Andrew J. Maniotis; Jeffrey M. Trent; Robert Folberg; Mary J.C. Hendrix
- Book ID
- 110338415
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 498 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0262-0898
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The molecular changes associated with the transition of melanoma cells from radial growth phase to vertical growth phase (metastatic phenotype) are not very well defined. Expression of the tyrosine-kinase receptor c-KIT progressively decreases during local tumor growth and invasion of human melanoma