Molecular cytogenetics of human papillomavirus-negative cervical carcinoma cell lines
โ Scribed by Drazen B. Zimonjic; Scott Simpson; Nicholas C. Popescu; Joseph A. DiPaolo
- Book ID
- 113253764
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 680 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0165-4608
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๐ SIMILAR VOLUMES
## Abstract We applied a combination of molecular cytogenetic methods, including comparative genomic hybridization (CGH), spectral karyotyping (SKY), and fluorescence in situ hybridization (FISH), to characterize the genetic aberrations in eight widely used cervical cancer (CC) cell lines. CGH iden
A total of six cervical carcinoma cell lines, of which two contained human papillomavirus (HPV) type 16 and four contained HPV type 18 DNA, were examined for viral RNA expression by spot-blot hybridization. All six cell lines contained HPV-specific cytoplasmic poly(A)-containing RNA. The same RNA sp