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Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor gene loci

✍ Scribed by Gesk, S; Martín-Subero, J I; Harder, L; Luhmann, B; Schlegelberger, B; Calasanz, M J; Grote, W; Siebert, R


Book ID
110055430
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
180 KB
Volume
17
Category
Article
ISSN
0887-6924

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## Abstract Mantle cell lymphoma (MCL) is genetically characterized by 11q13 translocations leading to the overexpression of __CCND1,__ and additional secondary genomic alterations that may be important in the progression of this disease. We have analyzed 22 MCL cases and 10 MCL cell lines using mu