𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular consequences of presenilin-1 mutation

✍ Scribed by Russo, C.; Schettini, G.; Saido, T. C.; Hulette, C.; Lippa, C.; Lannfelt, L.; Ghetti, B.; Gambetti, P.; Tabaton, M.; Teller, J. K.


Book ID
109774904
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
137 KB
Volume
411
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A novel presenilin 1 mutation (L174
✍ A. Bertoli Avella; B. Marcheco Teruel; J. Llibre Rodriguez; N. Gomez Viera; I. B πŸ“‚ Article πŸ“… 2002 πŸ› Springer 🌐 English βš– 343 KB
Presenilin-1 mutations in Alzheimer's di
✍ Gambetti, P.; Russo, C.; Schettini, G.; Saido, T. C.; Hulette, C.; Lippa, C.; La πŸ“‚ Article πŸ“… 2000 πŸ› Nature Publishing Group 🌐 English βš– 258 KB
Inhibition of AMPA responses by mutated
✍ AndrΓ©a M. Moerman; Steven W. Barger πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 168 KB

The inheritance of Alzheimer's disease in some families, as well as ablation/rescue genetics in mice, suggest that point mutations in the presenilin-1 (PS1) gene can cause disease through an unknown gain-of-function. While mutations associated with familial Alzheimer's can alter apoptotic rates and