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Molecular conformation of destruxin A

✍ Scribed by Sandeep Gupta; Donald W. Roberts; J.A.A. Renwick; Chao-Zhou Ni; Jon Clardy

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
346 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

The peptide backbone conformation of destruxin A in CDCl3, as studied by NOESY, closely resembles its crystal conformation which was deduced by a single crystal x-ray analysis.

The destruxins, insecticidal cyclodepsipeptides, were originally isolated from the entomogenous fungus Meiarhizium anisopliae. 1 Recently, destruxin B was isolated from the plant pathogenic fungus, Alternaria brassicag and roseotoxin B is known to be produced by Trichothecium roseum.3

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