Molecular cloning of U1 and U2 snRNP associated proteins

✍ Scribed by Peter T. Sillekens; Winand J. Habets; Walther J. Venrooij

• Publisher: Springer
• Year: 1987
• Tongue: English
• Weight: 32 KB
• Volume: 12
• Category: Article
• ISSN: 0301-4851
• DOI: 10.1007/bf00356877

✦ Synopsis

Sera from patients with Systemic Lupus Erythematosus (SLE) and Mixed Connective Tissue Disease (MCTD) often contain antibodies against the Useries of small nuclear rlbonucleoprotein particles (snRNPs). UI, U2, U5 and U4/U6 snRNPs contain a common core consisting of polypeptides B/B', D/D', E, F and G. UI snRNPs in addition