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Molecular Cloning of the akt Oncogene and Its Human Homologues AKT1 and AKT2: Amplification of AKT1 in a Primary Human Gastric Adenocarcinoma

โœ Scribed by Stephen P. Staal


Book ID
123634754
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
880 KB
Volume
84
Category
Article
ISSN
0027-8424

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AKT2, an oncogene encoding a protein serine-threonine kinase implicated in phosphatidylinositol-3-OH kinase signaling, is amplified in some human ovarian and pancreatic carcinomas. We previously demonstrated that the tumorigenicity and invasiveness of pancreatic ductal adenocarcinoma (PDAC) cell lin