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Molecular cloning of a novel gene involved in serotonin receptor-mediated signal transduction in rat stomach

✍ Scribed by Susumu Ohya; Takemasa Takii; Hiroko F. Yamazaki; Miki Matsumori; Kikuo Onozaki; Minoru Watanabe; Yuji Imaizumi


Book ID
119415663
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
887 KB
Volume
401
Category
Article
ISSN
0014-5793

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By using differential display, we cloned the human counterpart of the murine gene Hic-5 from senescent human keratinocytes. The full-length cDNA contained a short GC-stretch proceeding a consensus Kozak sequence followed by a single open reading frame of 1338 bp encoding a 461Β±amino acid protein wit