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Molecular cloning and sequencing of canine T-cell costimulatory molecule (CD28)

✍ Scribed by Tanvir.S. Khatlani; Zhiyong Ma; Masaru Okuda; Takafumi Onishi


Book ID
117335720
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
332 KB
Volume
78
Category
Article
ISSN
0165-2427

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T lymphocytes require two distinct signals for activation from antigen presenting cells . The first antigen-specific signal occurs when the T-cell receptor binds to antigenic peptides presented by major histocompatibility complex molecules. The second costimulatory signal occurs when CD28 and CTLA-4