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Molecular cloning and expression of rat aldolase C messenger RNA during development and hepatocarcinogenesis

✍ Scribed by Henriette SKALA; Magdeleine VIBERT; Eugenia LAMAS; Pascal MAIRE; Fabien SCHWEIGHOFFER; Axel KAHN


Book ID
115124989
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
627 KB
Volume
163
Category
Article
ISSN
1432-1327

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Cholesterol 7-hydroxylase is a rate-limiting enzyme in bile acid synthesis, a major pathway for cholesterol catabolism. It plays a crucial role in postnatal development and survival. In an adult liver, its activity and messenger RNA (mRNA) are heterogeneously distributed with concentration in the pe