Molecular cloning and enzymatic characterization of a class mu glutathioneS-transferase ofParagonimus westermani
✍ Scribed by Tae Yun Kim; Ji-Yun Lee; Tae Im Kim; Ki Ho Moon; Shin-Yong Kang; Sung-Jong Hong
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 434 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1432-1955
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## Abstract A cDNA clone coding for a mu‐class glutathione __S__‐transferase (GST) was isolated from a hepatopancreas cDNA library from the shrimp __Litopenaeus vannamei__. The deduced amino acid sequence (215 amino acids) has >50% identity to rodents and other mammals mu‐class GSTs. Using RT‐PCR,
## Abstract Glutathione __S__‐transferases (GSTs) are a family of detoxifying enzymes that catalyze the conjugation of glutathione (GSH) to electrophiles, thereby increasing the solubility of GSH and aiding its excretion from the cell. In this study, a glutatione __S__‐transferase from the gills of