CO binding study of mouse heme-regulated
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Jotaro Igarashi; Akira Sato; Teizo Kitagawa; Ikuko Sagami; Toru Shimizu
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Article
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2003
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Elsevier Science
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English
⚖ 177 KB
Heme-regulated eukaryotic initiation factor (eIF)-2alpha kinase (HRI) regulates the synthesis of globin chains in reticulocytes with heme availability. In the present study, CO binding kinetics to the 6-coordinated Fe(II) heme of the amino-terminal domain of mouse HRI and resonance Raman spectra of