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Molecular cloning and characterization of mouse mast cell chymases

✍ Scribed by Wei Chu; David A. Johnson; Phllip R. Musich

Book ID
113268894
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
508 KB
Volume
1121
Category
Article
ISSN
0167-4838

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Using a recently developed PCR-based strategy, a cDNA encoding a novel mouse mast cell (MC) serine protease (MMCP-8) was isolated and characterized. The MMCP-8 mRNA contains an open reading frame of 247 amino acids (aa), divided into a signal sequence of 18 aa followed by a 2-aa activation peptide (