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Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K+ channel Kv2.1

โœ Scribed by Yorikata Sano; Shinobu Mochizuki; Akira Miyake; Chika Kitada; Kohei Inamura; Hiromichi Yokoi; Katsura Nozawa; Hitoshi Matsushime; Kiyoshi Furuichi


Book ID
117103884
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
245 KB
Volume
512
Category
Article
ISSN
0014-5793

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We have cloned a novel voltage-gated K channel, LKv1, in two species of leech. The properties of LKv1 expressed in transiently transfected HEK293 cells is that of a delayed rectifier current. LKv1 may be a major modulator of excitability in leech neurons, since antibody localization studies show tha