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Molecular cloning and characterization of a novel isoform of the non-canonical poly(A) polymerase PAPD7

✍ Scribed by Ogami, Koichi; Cho, Rihe; Hoshino, Shin-ichi


Book ID
123263914
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
631 KB
Volume
432
Category
Article
ISSN
0006-291X

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## Abstract Toll-like receptor 9 (TLR9) is a component of the innate immune system, which recognizes the DNA of both pathogens and hosts. Thus, it can drive autoimmune diseases. Intracellular antibodies expressed inside the ER block transitory protein functions by inhibiting the translocation of th