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Molecular Characterization of the Tight Junction Protein ZO-1 in MDCK Cells

✍ Scribed by L. González-Mariscal; S. Islas; R.G. Contreras; M.R. Garcı&#x0301;a-Villegas; A. Betanzos; J. Vega; A. Diaz-Quiñónez; N. Martı&#x0301;n-Orozco; V. Ortiz-Navarrete; M. Cereijido; J. Valdés

Book ID: 115603213
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 503 KB
Volume: 248
Category: Article
ISSN: 0014-4827
DOI: 10.1006/excr.1999.4392

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## Abstract The formation of a barrier by tight junctions is important in epithelia of various tissues. Substance P (SP) and insulin‐like growth factor (IGF)–1 synergistically promote barrier function in the corneal epithelium. We have now examined the effects of SP and IGF‐1 on expression of the t