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Molecular Characterization of Mitomycin C-Induced Large Deletions and Tandem-Base Substitutions in the Bone Marrow of gpt delta Transgenic Mice

โœ Scribed by Takeiri, Akira; Mishima, Masayuki; Tanaka, Kenji; Shioda, Akihumi; Ueda, Otoya; Suzuki, Hiroshi; Inoue, Makoto; Masumura, Ken-ichi; Nohmi, Takehiko


Book ID
127070558
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
229 KB
Volume
16
Category
Article
ISSN
0893-228X

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Efficient detection of deletions induced
โœ Naoko Okada; Ken-ichi Masumura; Takehiko Nohmi; Nobuhiro Yajima ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 83 KB ๐Ÿ‘ 2 views

Transgenic rodent mutation assays permit the detection and molecular analysis of various types of gene mutations, such as base changes and frameshifts, in a number of tissues. It is reported, however, that deletion mutations are not efficiently detected by the assays, in particular those using lambd