This study was designed to identify the -thalassemia mutations in an Argentine population. Seventy-one pediatric patients and 101 available relatives were studied (85 chromosomes). Diagnosis of -thalassemia was made by conventional hematological procedures. Molecular studies were carried out by do
Molecular characterization of Hb S(C) β-thalassemia in American blacks
✍ Scribed by J. M. Gonzalez-Redondo; A. Kutlar; F. Kutlar; V. C. McKie; K. M. McKie; E. Baysal; Dr. T. H. J. Huisman
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 484 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The -thalassemia syndromes are a heterogeneous group of genetic disorders characterized by reduced or absent expression of the -globin gene. To date, over 300 -thalassemia alleles have been characterized in or around the -globin region. Thalassemia major is severe anemia necessitating chronic bl
In this report we describe the molecular analysis of 795 chromosomes derived from unrelated Turkish -thalassemia and sickle cell anemia carriers identified in hematology clinics in Istanbul, Ankara, Izmir, Adana, and Antalya. The determination of the molecular pathology of 754 -thalassemia and 42