Molecular characterization of genome of a novel human T-cell leukaemia virus
✍ Scribed by Chen, Irvin S. Y.; McLaughlin, Jami; Gasson, Judith C.; Clark, Steven C.; Golde , David W.
- Book ID
- 109732261
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 473 KB
- Volume
- 305
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/305502a0
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## Abstract Adult T‐cell leukaemia (ATL) is a neoplastic disease derived from CD4^+^ T‐lymphocytes and etiologically associated with human T‐cell leukaemia virus type I (HTLV‐I). In addition to structural genes, HTLV‐I encodes regulatory and accessory genes in the pX region. Among them, Tax is thou
## Abstract In order to assess the specificity and sensitivity of two peptide‐based assays (Synth^TM^ HTLV‐I and HTLV‐II enzyme‐linked immunoassay [EIA] [UBI] and Select‐HTLV^TM^ EIA [IAF]) in discriminating between antibody to HTLV‐I and HTLV‐II infection, a panel of 186 well‐characterised serum/p