Molecular mapping of chromosome 2 deleti
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Andrew Silver; John Moody; Rosemary Dunford; Debbie Clark; Sue Ganz; Robert Bulm
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Article
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1999
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John Wiley and Sons
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English
โ 224 KB
๐ 3 views
Radiation-induced acute myeloid leukemias (AMLs) in the mouse are characterized by chromosome 2 deletions. Previous studies showed that a minimal deleted region (mdr) of ฯณ6.5 cM is lost from one homologue in chromosome 2-deleted AMLs. An AML tumor suppressor gene is proposed to map within this mdr.