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Molecular Characterization of an Intragenic Minisatellite (VNTR) Polymorphism in the Human Parathyroid Hormone-Related Peptide Gene in Chromosome Region 12p12.1-p11.2

โœ Scribed by Zdenka Pausova; Kenneth Morgan; T.Mary Fujiwara; Johanne Bourdon; David Goltzman; Geoffrey N. Hendy


Book ID
115611681
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
141 KB
Volume
17
Category
Article
ISSN
0888-7543

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Radiation-induced acute myeloid leukemias (AMLs) in the mouse are characterized by chromosome 2 deletions. Previous studies showed that a minimal deleted region (mdr) of ฯณ6.5 cM is lost from one homologue in chromosome 2-deleted AMLs. An AML tumor suppressor gene is proposed to map within this mdr.