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Molecular characterization of a new member of the immunoglobulin superfamily that potentially functions in T-cell activation and development

โœ Scribed by D. M. Ruble; D. N. Foster


Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
445 KB
Volume
51
Category
Article
ISSN
0093-7711

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In this study we describe the functional and molecular characterization of IRp60 (inhibitory receptor protein 60), an inhibitory receptor expressed on all human NK cells. The IRp60 molecule has been identified by the generation of three novel monoclonal antibodies (mAb). Cross-linking of IRp60 by sp