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Molecular characterization of a Dictyostelium G-protein α-subunit required for development

✍ Scribed by Maureen A Brandon; Susan Voglmaier; A.Afshan Siddiqi


Book ID
117522641
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
414 KB
Volume
200
Category
Article
ISSN
0378-1119

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Phosphorylation of the G protein α-subun
✍ Robert E. Gundersen 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB 👁 1 views

The Ga2-subunit of Dictyostelium discoideum is essential to the initial stage of the cell's developmental life cycle. In response to the extracellular chemoattractant, cAMP, Ga2 is activated and transiently phosphorylated on serine-113 [Chen et al. (1994): J Biol Chem 269:20925-20930]. The role of G