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Molecular Chaperones || Chaperonins and Protein Folding: Unity and Disunity of Mechanisms [and Discussion]

✍ Scribed by George H. Lorimer, Matthew J. Todd, Paul V. Viitanen, N. C. Price, R. Jaenicke, F.-U. Hartl, R. B. Freedman, M. Yoshida, W. J. Welch and B. O'Hara

Book ID: 123646659
Publisher: The Royal Society
Year: 1993
Tongue: English
Weight: 1009 KB
Volume: 339
Category: Article
ISSN: 0080-4622
DOI: 10.2307/55826

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## Abstract The discovery of “molecular chaperones” has dramatically changed our concept of cellular protein folding. Rather than folding spontaneously, most newly synthesized polypeptide chains seem to acquire their native conformation in a reaction mediated by these versatile helper proteins. Und