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Molecular biomarkers for the study of childhood leukemia

✍ Scribed by Martyn T. Smith; Cliona M. McHale; Joseph L. Wiemels; Luoping Zhang; John K. Wiencke; Shichun Zheng; Laura Gunn; Christine F. Skibola; Xiaomei Ma; Patricia A. Buffler

Book ID
113923531
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
690 KB
Volume
206
Category
Article
ISSN
0041-008X

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Childhood leukemia is the commonest form of childhood cancer and represents clonal proliferation of transformed hemopoietic cells as a result of genetic changes. Molecular characterization of these changes, in particular chromosomal translocations, has yielded a wealth of information on the mechanis