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Molecular Biology: Reverse Transcriptase, the DNA Polymerase of Oncogenic RNA Viruses

✍ Scribed by GALLO, ROBERT C.


Book ID
109679765
Publisher
Nature Publishing Group
Year
1971
Tongue
English
Weight
619 KB
Volume
234
Category
Article
ISSN
0028-0836

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Differential inhibition of DNA polymeras
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Three potential inhibitors of reverse transcriptase activities, phosphonoformate (PF), phosphonoacetate (PAA), and ethyl-diethyl phosphonoformate (Et-PF), were compared in this study. Only PF was found to inhibit the DNA polymerase activity of the purified reverse transcriptase of Moloney murine leu