๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Molecular Biology of Alzheimer's Disease

โœ Scribed by Muller-Hill, B; Beyreuther, K

Book ID
121430688
Publisher
Annual Reviews
Year
1989
Tongue
English
Weight
764 KB
Volume
58
Category
Article
ISSN
0066-4154

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โœฆ Synopsis

The amyloid first seen by Alois Alzheimer in the brain of a deceased demented patient (1) turned out to be an extraordinary challenge for biochem ists and molecular biologists alike. The extreme insolubility of this polypeptide first challenged the protein chemists attempting to sequence it (2, 3). Then Ithe questions arose: Was the amyloid the product of a slow virus (4) or was it the product of a human gene? If the latter, did the structure of its 287

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