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Molecular Basis of the Voltage-Dependent Gating of TREK-1, a Mechano-Sensitive K+ Channel

✍ Scribed by François Maingret; Eric Honoré; Michel Lazdunski; Amanda Jane Patel

Book ID
118286784
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
258 KB
Volume
292
Category
Article
ISSN
0006-291X

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✍ Kuo-Long Lou; Po-Tsang Huang; Yu-Shuan Shiau; Yuh-Yuan Shiau 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB

## Abstract The carboxyl terminus of S3 segment (S3~C~) in voltage‐gated potassium channels was proposed to bear the binding site for gating modifier toxins like Hanatoxin and a helical secondary structural arrangement was suggested. Due to the lack of complete structure in high resolution for such