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Molecular basis of the inflammatory response to adenovirus vectors

โœ Scribed by Liu, Q; Muruve, D A


Book ID
110039335
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
107 KB
Volume
10
Category
Article
ISSN
0969-7128

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Background The major concern for the use of adenoviral vectors for gene therapy is the viral-induced immune response that has been shown to be responsible for short-term transgene expression and inefยฎcient viral readministration. In vivo studies and clinical trials with recombinant adenovirus have s