Dose-dependent inhibition of phospholipa
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G. Petroianu; U. Helfrich; A. Schmitt; W. Bergler; R. RΓΌfer
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Article
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1997
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John Wiley and Sons
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English
β 52 KB
To establish the dose dependency of phospholipase A 2 (PLA 2 ) inhibition by the organophosphorus compound (OPC) paraoxon (POX), human platelet membranes were incubated after Ca 2+ removal (to inactivate the PLA 2 ) with 0.3, 1 and 3 g ml Ψ1 POX for 5, 30 and 60 min each. The PLA 2 activity (pmol mg