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Molecular basis of chromosome movement

โœ Scribed by Hyman, Anthony A.; Mitchison, Timothy J.

Book ID
122377689
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
480 KB
Volume
2
Category
Article
ISSN
0959-440X

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Molecular basis of chromosome movement
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The effects of mouse satellite, main band and total DNA on the fluorescence intensity of quinacrine and of the bibenzimidazole derivative Hoechst 33258 were tested in solution. No significant differences were noticed between the double-stranded DNAs in spite of the 5% difference in AT-content betwee

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Silver and mercury ions are known to react with the bases of nucleic acids in solution. At low cation/base ratios Ag+ has an affinity for GC pairs in DNA, whereas Hg++ is preferentially bound to AT-rich nucleic acids. We have used fluorometry to measure the effect of these cations on the fluorescenc