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Molecular basis of androgen insensitivity

✍ Scribed by Brüggenwirth, H.T.; Boehmer, A.L.M.; Verleun-Mooijman, M.C.T.; Hoogenboezem, T.; Kleijer, W.J.; Otten, B.J.; Trapman, J.; Brinkmann, A.O.


Book ID
120656985
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
704 KB
Volume
58
Category
Article
ISSN
0960-0760

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Molecular basis of androgen insensitivit
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Androgen insensitivity syndromes (AIS) are due to end-organ resistance to androgenic steroids in males leading to defective virilization of the external genitalia. The phenotype encompasses a wide array of genital ambiguity and may range from completely female to undervirilized but unequivocally mal