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Molecular Basis of 4-Nitroquinoline 1-Oxide Carcinogenesis

✍ Scribed by Bailleul, Bernard ;Daubersies, Pierre ;Galiègue-Zouitina, Sylvie ;Loucheux-Lefebvre, Marie-Henriette

Book ID: 108578843
Publisher: Wiley (Blackwell Publishing)
Year: 1989
Tongue: English
Weight: 437 KB
Volume: 80
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1989.tb01698.x

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## Abstract In this study we explored the mutation types of __p16^CDKN2A^__ exon 1 and the corresponding frequencies in experimental rat tongue carcinogenesis. Twenty barrier Sprague–Dawley (SD) rats were divided into the control (__n__ = 5) and experimental group (__n__ = 15), to which 4‐nitroquin