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Molecular basis for membrane selectivity of NK-2, a potent peptide antibiotic derived from NK-lysin

✍ Scribed by Hannah Schröder-Borm; Regine Willumeit; Klaus Brandenburg; Jörg Andrä

Book ID
117048260
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
369 KB
Volume
1612
Category
Article
ISSN
0005-2736

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Membrane association and selectivity of
Membrane association and selectivity of the antimicrobial peptide NK-2: a molecular dynamics simulation study
✍ Jutarat Pimthon; Regine Willumeit; Andreas Lendlein; Dieter Hofmann 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 875 KB

## Abstract In an effort to better understand the initial mechanism of selectivity and membrane association of the synthetic antimicrobial peptide NK‐2, we have applied molecular dynamics simulation techniques to elucidate the interaction of the peptide with the membrane interfaces. A homogeneous d