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Molecular Basis for Membrane Pore Formation by Bax Protein Carboxyl Terminus

✍ Scribed by Tatulian, Suren A.; Garg, Pranav; Nemec, Kathleen N.; Khaled, Annette R.

Book ID
119209798
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
37 KB
Volume
102
Category
Article
ISSN
0006-3495

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Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid mem