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Molecular basis and thrombotic manifestations of antithrombin deficiency in 15 unrelated Chinese patients

✍ Scribed by Ding, Qiulan; Wang, Min; Xu, Guanqun; Ye, Xu; Xi, Xiaodong; Yu, Tingting; Wang, Xuefeng; Wang, Hongli

Book ID
121681050
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
800 KB
Volume
132
Category
Article
ISSN
0049-3848

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## Abstract Antithrombin (AT), the most important coagulation serine proteases inhibitor, plays an important role in maintaining the hemostatic balance. Inherited AT deficiency, mainly characterized by predisposition to recurrent venous thromboembolism, is transmitted in an autosomal dominant manne