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Molecular assessment of dhfr/dhps mutations among Plasmodium vivax clinical isolates after introduction of sulfadoxine/pyrimethamine in combination with artesunate in Iran

✍ Scribed by Mandana Afsharpad; Sedigheh Zakeri; Sakineh Pirahmadi; Navid D. Djadid


Book ID
113798061
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
210 KB
Volume
12
Category
Article
ISSN
1567-1348

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To overcome the declining efficacy of the 4-aminoquinolines in Papua New Guinea, sulfadoxine/pyrimethamine (SP) was combined with the 4-aminoquinolines as the first line treatment for falciparum malaria since 2000. To assess how this change had affected SP resistant gene polymorphisms, we determined