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Molecular aspects of human disease: 2 volumes

โœ Scribed by Scriver, Charles R.


Book ID
122913207
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
295 KB
Volume
1
Category
Article
ISSN
1043-2760

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Huntington's disease (HD) is a progressive neurodegenerative disease striking principally medium spiny GABAergic neurons of the caudate nucleus of the basal ganglia. It affects about one in 10,000 individuals and is transmitted in an autosomal dominant fashion. The molecular basis of the disease is