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Molecular and functional aspects of anionic channels activated during regulatory volume decrease in mammalian cells*

✍ Scribed by J. Fürst; M. Gschwentner; M. Ritter; G. Bottà; M. Jakab; M. Mayer; L. Garavaglia; C. Bazzini; S. Rodighiero; G. Meyer; S. Eichmüller; E. Wöll; M. Paulmichl


Publisher
Springer
Year
2002
Tongue
English
Weight
261 KB
Volume
444
Category
Article
ISSN
0031-6768

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Biphasic rises in cytosolic free Ca2+in
✍ Akihiro Hazama; Yasunobu Okada 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 535 KB

During exposure to a hypotonic solution (55% osmolarity), cultured human epithelial (Intestine 407) cells exhibit a regulatory volume decrease after osmotic swelling. This process is known to involve parallel activation of volume-regulatory K + and C1-conductances. Biphasic increase in the cytosolic