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Molecular and Fluorescence In Situ Hybridization Characterization of the Breakpoints in 46 Large Supernumerary Marker 15 Chromosomes Reveals an Unexpected Level of Complexity

✍ Scribed by S.E. Roberts; F. Maggouta; N.S. Thomas; P.A. Jacobs; J.A. Crolla


Book ID
117854324
Publisher
American Society of Human Genetics
Year
2003
Tongue
English
Weight
425 KB
Volume
73
Category
Article
ISSN
0002-9297

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## Abstract We have further characterized an unusual 22p+ marker chromosome with a double nucleolus organizer region (dNOR) previously identified in a family with late‐onset dementia of the Alzheimer type. G‐banding and morphology of the marker's q arm were typically normal. However, the p+ arm ha