Molecular and cytogenetic response of chronic myelogenous leukemia treated with imatinib mesylate: one institutional experience in Japan
β Scribed by Yasuhito Nannya; Hiromitsu Yokota; Yumiko Sato; Go Yamamoto; Takashi Asai; Motoshi Ichikawa; Takuro Watanabe; Keiki Kumano; Akira Hangaishi; Tsuyoshi Takahashi; Shigeru Chiba; Yutaka Yatomi; Mineo Kurokawa
- Book ID
- 107618562
- Publisher
- Carden Jennings Publishing
- Year
- 2008
- Tongue
- English
- Weight
- 255 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0925-5710
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## Abstract ## BACKGROUND Obtaining a major (Philadelphia chromosome [Ph] of < 35%) or a complete cytogenetic response (Ph of 0%) has been associated with excellent longβterm survival. Cytogenetic response may continue to improve with therapy. Because early allogeneic stem cell transplantation (SC
## Abstract ## BACKGROUND A T cell lymphoid blastic phase of chronic myelogenous leukemia (CML) is a rare occurrence, with only a few reported cases worldwide. Standard therapy for such patients is undetermined. Imatinib mesylate, a BcrβAbl tyrosine kinase inhibitor, has shown activity in CML. ##