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Molecular and cytogenetic investigation of complex tissue-specific duplication and loss of chromosome 21 in a child with a monosomy 21 phenotype

✍ Scribed by Krasikov, Natalie ;Takaesu, Norma ;Hassold, Terry ;Knops, Judith F. ;Finley, Wayne H. ;Scarbrough, Paula


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
685 KB
Volume
43
Category
Article
ISSN
0148-7299

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Molecular analysis of chromosome 21 in a
✍ Ahlbom, Bodil Edman; Goetz, Peter; Korenberg, Julie R.; Pettersson, Ulf; Seemano πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 68 KB

Down syndrome (DS) is caused in most cases by the presence of an extra chromosome 21. It has been shown that the DS phenotype is produced by duplication of only a small part of the long arm of chromosome 21, the 21q22 region, including and distal to locus D21S55. We present molecular investigations