## Communicated by Jurgen Horst Autosomal recessive polycystic kidney disease (ARPKD) is an important cause of childhood renal-and liverrelated morbidity and mortality. The clinical spectrum is widely variable. About 30 to 50% of affected individuals die in the neonatal period, while others survive
Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD)
β Scribed by William E. Sweeney; Ellis D. Avner
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 577 KB
- Volume
- 326
- Category
- Article
- ISSN
- 0302-766X
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Autosomal recessive polycystic kidney disease (ARPKD) is one of the most common hereditary renal cystic diseases and has a high infant mortality. Prenatal diagnosis using fetal sonography can be unreliable, especially in early pregnancy. The ARPKD locus has been mapped to proximal chromosome 6p allo
## Communicated by A. Jamie Cuticchia Autosomal recessive polycystic kidney disease (ARPKD) is an important cause of childhood renal-and liverrelated morbidity and mortality with variable disease expression. While most cases manifest peri-/neonatally with a high mortality rate in the first month of
## Background: Autosomal-recessive polycystic kidney disease (arpkd) is an important neonatal nephropathy characterized by fusiform dilation of collecting ducts, congenital hepatic fibrosis, and in some cases caroli's disease. the arpkd gene, pkhd1, has recently been identified. herein we describe
## Communicated by Jurgen Horst Autosomal recessive polycystic kidney disease (ARPKD) is one of the most common hereditary renal cystic diseases in children. The clinical spectrum ranges from stillbirth and neonatal demise to survival into adulthood. In a given family, however, patients usually di