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Molecular and Biophysical Characterization of Assembly-Starter Units of Human Vimentin

✍ Scribed by Norbert Mücke; Tatjana Wedig; Andrea Bürer; Lyuben N. Marekov; Peter M. Steinert; Jörg Langowski; Ueli Aebi; Harald Herrmann


Book ID
116661306
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
836 KB
Volume
340
Category
Article
ISSN
0022-2836

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Molecular modeling of vimentin filament
✍ Downing, Donald Talbot 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 931 KB

Intermediate-filament forming proteins are known to form rod-shaped dimers that are calculated to be 45 nm in length. Molecular modeling indicates that the dimerization is promoted by interchain hydrophobic interactions between sections of (Y helix and p helix. Further aggregation involves the forma