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Molecular and biochemical elucidation of a cellular phenotype characterized by adenine analogue resistance in the presence of high levels of adenine phosphoribosyltransferase activity

โœ Scribed by Nada H. Khattar; Gregory E. Cooper; Debra L. DiMartino; Peggy L. Bishop; Mitchell S. Turker

Publisher
Springer
Year
1992
Tongue
English
Weight
787 KB
Volume
30
Category
Article
ISSN
0006-2928

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A new method for the determination of adenine phosphoribosyltransferase activity in human erythrocytes by reversed phase high performance liquid chromatography
โœ Tsukasa Kojima; Toshihiro Nishina; Motoshi Kitamura; Hisashi Yamanaka; Kusuki Ni ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 421 KB ๐Ÿ‘ 2 views

A new method for the determination of adenine phosphoribosyltransferase (APRT) activity in human erythrocytes is described. APRT activity was assayed by a non-radiochemical method in which adenosine mnnophosphate (AMP) and AMY metabolites produced from a substrate adenine were converted to inosine b